Sarani Bio-Integra, Kanakapura Main Road, Konanakunte Cross, Bangalore

Skin Care

Sarani Bio-Integra undertakes research on the various Skin Care products like Moisturizers, Sun Screen, Skin Ointments, Cream before it is released in the market.

Skin Care

In vitro antioxidant studies.
Cytoprotective effect against UV induced cell damage.
Modulatory effect on collagen biosynthesis in dermal fibroblasts.
Evaluation of modulatory effect on Collagen, Elastin and MMP-9 gene expression in dermal fibroblasts

Skin Lightening

Evaluation of melanin inhibitory properties against FSK/UV induced melanogenesis.
Determination of Tyrosinase inhibitory activity
Evaluation of melanin inhibitory properties against UV induced melanin synthesis.
In vitro antioxidant activity (LPO)

Skin Hydration

In vitro antioxidant studies.
Cytoprotective effect against UV induced cell damage.
In vitro cytoprotective activity against UV induced DNA damage in keratinocytes.
In vitro anti-inflammatory studies.
Evaluation of modulatory effect on AQP-3 and p53 gene expression in keratinocytes

Sun Screen

In vitro cytoprotective activity against UV induced DNA damage in keratinocytes.
In vitro anti-inflammatory studies.
Determination of SPF values of products as per standard guideline.
Evaluation of product potential against UV induced photo-aging.

Anti-acne

In vitro inhibitory studies against P. acne.
In vitro anti-inflammatory studies
Evaluation of modulatory effect on 5α reductase, IL-8 and MMP-1 gene expression

Skin Profiling and Sensory Studies:

We have expertise in understanding local cultures and traditions, which is crucial when designing subject questionnaires to provide accurate and informative result, pertinent to the study population in question.

Services on Sites include the following:

Profiling studies are key to understand skin, hair attributes of a target population and cultural, socio-economic, habitual impact on these attributes.
Effects of various pollutants on skin
Diabetic skin profiling

Profiling / perception of various skin care products
Skin care habits
Skin profiling of the Indian skin population

Efficacy and Claim Support:

Area	Description	How	Outcome / support
Skin related	Pigmentation, anti-aging, anti-tanning or spa therapy	Dermatologist’s evaluation, specialized instrument evaluation, the subject’s feedback and imaging	Efficacy of Pigmentation Correction Products Efficacy of Anti Aging Products Efficacy of Acne Products Efficacy of Melasma Products Efficacy of Anti-Wrinkle Products Kinetic Studies