Infrastructure of Sarani Bio-Integra

The preclinical lab of Sarani Bio-Integra is in collaboration  with the  Department of Molecular Medicine, St. John’s Research Institute, Bangalore. For the clinical research studies it has a collaboration with different professional labs.

The preclinical lab of Sarani Bio-Integra is in collaboration with the  Department of Molecular Medicine, St. John’s Research Institute, Bangalore.

Brief introduction to the facilities:

St. John’s Research Institute (SJRI) is an integral part of the St. John’s Academy of Health Sciences that is administered by the Catholic Bishops Conference of India (CBCI) and was started in year 2004. Vision of the institute is to improve health of the community through research and development of a center for excellence in Medical Research. Division of Molecular medicine within SJRI comprises of the Cell biology, Molecular Biology Research group, Genetics, Clinical Proteomics and Oncology.

We have established a state-of-the-art molecular diagnostics lab with a full range of molecular platforms including Next-Gen-Sequencing, Real time PCR, Molecular pathology, Tissue culture and flow cytometry. The institute also has a world class biorepository with liquid N2 storage facility for clinical samples that is monitored round the clock. SJRI has a fully equipped Animal house with permits to work on small animals and registered under CPCSEA.In addition to the patient specimen centric work we have established experimental mammalian cell culture facilities and individually-ventilated –caging-systems to establish patient derived Xenografts (PDX). Using these approaches we have explored mechanisms of chemo resistance and metastasis mediated via tumor stroma interaction.

In the proteomics division, the major biophysical techniques used include absorption and emission spectroscopy and mass spectrometry. Clinically important biomarkers can be screened in the biological fluid, using mass spectrometry based proteomics. Cell culture group is interested in probing the basic biology of various biomolecules using the tissue culture facility and invitro models from the wide array of cell lines available at our Cell line Biorepository

Oncology research group is interested in establishing the long-term outcomes in women treated for breast cancer and the molecular correlates of these outcomes.We have been the recipient of two 10-year philanthropic grants in addition to other extramural grants that have enabled such long-term un-interrupted activity. We currently also have National and International grants supporting our work including the most prestigious Welcome-DBT intermediate fellowship.

We have a unique advantage of a full time pathologist, molecular biologists, bioinformaticians and bio statisticians working in the Research facility .With our current scientific and technical expertise, we are primed to undertake industry liaised collaborations for various projects such as drug screening, testing of compounds of therapeutic value on a range of in-vivo and in-vitro model systems and big data analysis.

Clinical Development and Medical Affairs

Experienced Clinical development team
Enrolment as per protocol requirements
Qualified and experienced scientific writers

Clinical Trial and Studies covered are:

  • Safety study of the cosmetics/products
  • Efficacy study of the cosmetics / products

Service Offerings:

  • Project management for Phase II and III clinical studies for Consumer care and Nutrition products 

Study types:

  • Clinical end point studies
  • Diagnostics/ Devices
  • Derma studies

Advantages of Clinical studies :

  • Services are backed by state-of-the-art equipment technology
  • Expert clinicians/highly qualified and senior Doctors/ Consultants. Friendly and warm environment.

Our Strengths:

  • Modern State of the art Equipment with Fully automated analyzers/equipment
  • Highly qualified/ Experienced staff
  • Providing all clinical and Diagnostic services under one roof Going for accreditation

The overview of the clinical trials procedure:

  • Test protocols in line / aligned with the international guidelines.
  • Scale of measurements developed in accordance with the Caucasian skin type, and are supported by our clear understanding of the Indian skin type.
  • Improvised and standardized testing techniques and protocols in line with regulations, contemporary research requirements, product formulation and adjuvant methods.
  • Ability to cater to the needs and requirements of our clients in India, with regards to 24/48 hrs occlusive patch test, HRIPT, open application tests and stinging test, among many others.
  • With a dedicated area for skin evaluation, grooming, dental evaluation, skin sensitivity evaluation and imaging.
  • Equipment & Specialized Instruments specifically used for derma products and include hydration, elasticity, melanin, erythema, TEWL, and Digital camera devices among others

Services in Clinical Studies

  • Dermatology and Cosmetology studies
  • Diet, Nutrition, Weight
  • All Specialty Consultation
  • Cosmetology Consultation